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Pulmonology: Obstructive, Restrictive & ABG Analysis

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Spirometry Comparison: How do FEV1/FVC ratio, FVC, and Total Lung Capacity (TLC) differentiate Obstructive vs. Restrictive lung disease?

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Spirometry Diagnostic Criteria:

ParameterObstructive (Asthma, COPD)Restrictive (IPF, Sarcoidosis)
FEV1/FVC Ratio< 0.70 (< 70%) (Hallmark!)Normal or Increased ($\ge 0.70$)
FEV1Markedly $\downarrow\downarrow$$\downarrow$ (proportionate to FVC)
FVCNormal or slightly $\downarrow$Markedly $\downarrow\downarrow$
TLC (Gold Standard)Increased (Air trapping)$\downarrow < 80%$ predicted
Residual Volume (RV)IncreasedDecreased
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